RESUMO
OBJECTIVES: Ventricular assist devices have been widely accepted as an alternative treatment for advanced heart failure, while heart transplantation is a limited procedure because of the shortage of donors. In face of a scarce availability of these devices, many centers around the world have developed their own technologies. The Institute Dante Pazzanese of Cardiology holds a dedicated engineering center for mechanical circulatory support, being responsible for creating several prototypes and notable devices, like the first Brazilian artificial heart. The objectives of this study were to provide both a historical overview and a detailed characterization of each original device developed by the center. METHODS: We describe historical and technical features of the main ventricular assist devices developed at the Institute Dante Pazzanese of Cardiology through a focused review on the institute's scientific and technical production on ventricular assist devices or blood pumps, from 1990 to 2022, indexed in the electronic databases Latin American and Caribbean Health Sciences Literature (LILACS), PubMed, and the Scientific Electronic Library Online (SciELO). RESULTS: The following devices were selected from the review: (1) The Spiral Pump is a disposable centrifugal pump with an internal conically shaped rotor, a spiral impeller, which carries threads on its surface. The device was designed for cardiopulmonary bypass in 1992, passed through consecutive design modifications and preclinical tests until approval for clinical application in 2007. (2) The Auxiliary Total Artificial Heart is an electromechanical pulsatile blood pump with left and right chambers, originally designed in 1995 to work as a heterotopic artificial heart. Preclinical studies evaluated hydrodynamic performance in mock circulatory loops and in vivo implants were performed in calves from 1999 to 2009. In 2012, it became the first nationally conceived artificial heart approved for clinical trials in Brazil. (3) The Implantable Centrifugal Blood Pump was conceived in 2006 for long-term circulatory assistance with a unique impeller design concept producing a mixed flow. Preclinical studies included hydrodynamic and hemolysis tests, analysis in a hybrid cardiovascular simulator and anatomical positioning in calves. (4) The Apico-Aortic Blood Pump consists of a miniaturized centrifugal pump originally conceived in 2012 for bridge to transplantation strategy. Preclinical studies included hydrodynamic and hemolysis tests, analysis in a hybrid cardiovascular simulator and anatomical positioning in pigs. (5) The Temporary Circulatory Support Device is a new centrifugal blood pump for temporary ventricular assistance developed with the purpose of bridge to decision or bridge to recovery strategies. Originally conceived in 2013, preclinical studies on the device consisted only of hydrodynamic and hemolysis tests. CONCLUSION: From the academic point of view, Brazil count on a few groups with a considerable output in ventricular assist device research and development. Notable devices produced at Institute Dante Pazzanese of Cardiology, from a total artificial heart to varied and innovative centrifugal pumps, have demonstrated excellent results for future clinical applications. More financial and institutional support are needed for the continuation of these promising research projects.
RESUMO
OBJECTIVE: To describe a new technique of sternal closure, modified from the conventional figure-of-eight approach, which can provide a secure closure and prevent sternal complications. METHODS: The modified technique is based on the intercalation of the caudal portion of each steel wire passed along the sternum. This is a retrospective analysis of patients operated with this modified technique at our institution between January 2014 and December 2016. RESULTS: One hundred and forty-three patients underwent sternal closure with the modified technique. In-hospital mortality rate was 1.4% (n=2). No sternal instability was observed at 30 days postoperatively. Two patients developed mediastinitis that required extraction of the wires. CONCLUSION: Short-term results have shown that the modified sternal closure technique can be used safely and effectively, with complications rates being consistent with worldwide experience.
Assuntos
Esterno/cirurgia , Deiscência da Ferida Operatória/prevenção & controle , Técnicas de Sutura/instrumentação , Técnicas de Fechamento de Ferimentos/instrumentação , Adolescente , Adulto , Idoso , Fios Ortopédicos/efeitos adversos , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Masculino , Mediastinite/complicações , Pessoa de Meia-Idade , Complicações Pós-Operatórias/prevenção & controle , Período Pós-Operatório , Estudos Retrospectivos , Fatores de Risco , Deiscência da Ferida Operatória/etiologia , Técnicas de Sutura/efeitos adversos , Técnicas de Fechamento de Ferimentos/mortalidade , Adulto JovemRESUMO
Abstract Objective: To describe a new technique of sternal closure, modified from the conventional figure-of-eight approach, which can provide a secure closure and prevent sternal complications. Methods: The modified technique is based on the intercalation of the caudal portion of each steel wire passed along the sternum. This is a retrospective analysis of patients operated with this modified technique at our institution between January 2014 and December 2016. Results: One hundred and forty-three patients underwent sternal closure with the modified technique. In-hospital mortality rate was 1.4% (n=2). No sternal instability was observed at 30 days postoperatively. Two patients developed mediastinitis that required extraction of the wires. Conclusion: Short-term results have shown that the modified sternal closure technique can be used safely and effectively, with complications rates being consistent with worldwide experience.
Assuntos
Humanos , Masculino , Feminino , Lactente , Pré-Escolar , Criança , Adolescente , Adulto , Pessoa de Meia-Idade , Idoso , Adulto Jovem , Esterno/cirurgia , Deiscência da Ferida Operatória/prevenção & controle , Técnicas de Sutura/instrumentação , Técnicas de Fechamento de Ferimentos/instrumentação , Complicações Pós-Operatórias/prevenção & controle , Período Pós-Operatório , Deiscência da Ferida Operatória/etiologia , Fios Ortopédicos/efeitos adversos , Estudos Retrospectivos , Fatores de Risco , Técnicas de Sutura/efeitos adversos , Técnicas de Fechamento de Ferimentos/mortalidade , Mediastinite/complicaçõesRESUMO
A 76-year-old man with situs inversus totalis underwent a successful off-pump three-vessel coronary artery bypass surgery. The postoperative course was uneventful, and the patient was discharged 8 days later. At 9-month follow-up a coronary computed tomography angiography confirmed the viability of all of the grafts, and one year after the operation the patient remained asymptomatic. It comprises the fifth Brazilian case of a coronary surgery in a patient with situs inversus totalis and the first one of the country of a coronary artery bypass surgery without the use of the cardiopulmonary bypass in this condition.
Assuntos
Ponte de Artéria Coronária sem Circulação Extracorpórea/métodos , Dextrocardia/cirurgia , Situs Inversus/cirurgia , Idoso , Anastomose Cirúrgica/métodos , Brasil , Humanos , MasculinoRESUMO
Abstract A 76-year-old man with situs inversus totalis underwent a successful off-pump three-vessel coronary artery bypass surgery. The postoperative course was uneventful, and the patient was discharged 8 days later. At 9-month follow-up a coronary computed tomography angiography confirmed the viability of all of the grafts, and one year after the operation the patient remained asymptomatic. It comprises the fifth Brazilian case of a coronary surgery in a patient with situs inversus totalis and the first one of the country of a coronary artery bypass surgery without the use of the cardiopulmonary bypass in this condition.
Assuntos
Humanos , Masculino , Idoso , Situs Inversus/cirurgia , Ponte de Artéria Coronária sem Circulação Extracorpórea/métodos , Dextrocardia/cirurgia , Brasil , Anastomose Cirúrgica/métodosRESUMO
A 23-year-old man suffered a penetrating injury caused by a metallic fragment thrown from a grass-cutting tool, resulting in perforating injuries in the stomach, diaphragm, heart, and lungs.
Assuntos
Diafragma/lesões , Traumatismos Cardíacos/cirurgia , Lesão Pulmonar/cirurgia , Traumatismo Múltiplo/cirurgia , Estômago/lesões , Ferimentos Penetrantes/cirurgia , Diafragma/cirurgia , Traumatismos Cardíacos/diagnóstico por imagem , Humanos , Lesão Pulmonar/diagnóstico por imagem , Masculino , Estômago/cirurgia , Tomografia Computadorizada por Raios X , Resultado do Tratamento , Adulto JovemRESUMO
Penetrating cardiac trauma carries high mortality rates. It has been commonly associated with stabbing, but increasing urban violence has led to growing numbers of gunshot heart wounds. The latter have higher mortality rates among penetrating cardiac injuries and may affect multiple heart chambers, with mortality rates even higher. We report a patient, victim of an attempted armed robbery, who had a transfixing gunshot wound to the heart, successfully operated at our institution.
Assuntos
Traumatismos Cardíacos/etiologia , Ferimentos por Arma de Fogo/complicações , Adulto , Emergências , Traumatismos Cardíacos/cirurgia , Humanos , Masculino , Toracotomia , Resultado do Tratamento , Ferimentos por Arma de Fogo/cirurgiaRESUMO
O trauma cardíaco penetrante apresenta altas taxas de mortalidade. É comumente associado a lesões por armas brancas, porém crescentes índices na violência urbana têm contribuído para o aumento no número de ferimentos cardíacos por projéteis de armas de fogo. Estas possuem as maiores taxas de mortalidade dentre os ferimentos cardíacos penetrantes e podem acometer múltiplas câmaras cardíacas, com índices de mortalidade ainda mais elevados. Apresentamos um caso de um paciente, vítima de tentativa de roubo, que sofreu ferimento cardíaco transfixante por projétil de arma de fogo, operado com sucesso em nossa instituição.
Penetrating cardiac trauma carries high mortality rates. It has been commonly associated with stabbing, but increasing urban violence has led to growing numbers of gunshot heart wounds. The latter have higher mortality rates among penetrating cardiac injuries and may affect multiple heart chambers, with mortality rates even higher. We report a patient, victim of an attempted armed robbery, who had a transfixing gunshot wound to the heart, successfully operated at our institution.